Projects for 2026

Applications for 26/27 start projects has now closed. If you have any questions about future opportunities then please get in touch using the contacts page.

University of Leeds

Click on the project title to view the full description on the FindAPhD website.

ProjectPrimary supervisor
Single-Molecule Nanoinjection to Unveil Cellular functions of long non-coding RNAsEric Hewitt
Analysing the glycan coat of neurons with nanopipettesPaolo Actis
Astrocytes, Endozepines, and Insulin: A Brainstem Pathway for Metabolic ControlBeatrice Maria Filippi
BrainBatch: Harmonising EEG for Population NeuroscienceFaisal Mushtaq
Chikungunya Virus Defective Viral Genomes: Unravelling mechanisms of formation, immune modulation and effect on viral pathogenesisAndrew Tuplin
Decoding RNA Translation from Direct-FRAC-Seq Data with AI-Enhanced Graphical ModelsLuisa Cutillo
Illuminating Ras signalling: Imaging membrane complexes with synthetic protein probes and super-resolution microscopyDarren Tomlinson
Motor function preservation in ageingJessica Kwok
Reprogramming Meiotic Recombination for Accelerated Crop BreedingNatasha Yelina
Strategies to balance solar energy harvesting and photoprotection in biomembranes from plants and bacteriaPeter Adams
Understanding how the localisation of ribosome populations contributes to translational regulationJulie Aspden
Understanding protein phosphorylation networks across organisms: an integrated chemical, cell and computational biology approachAdam Nelson
Understanding the role of DEAD-box helicases in virus infectionAdrian Whitehouse
Unraveling the biology and signalling potential of sparse cell antigens through single-molecule flow cytometryAleks Ponjavic
Unravelling the mechanisms of cardiac myosin function in health and diseaseCharlie Scarff
Vascular-muscle crosstalk through Piezo1 as a mechanosensor regulating skeletal muscle adaptation to exerciseScott Bowen
The Role of Cholesterol Homeostasis and Regulation of Drug and Nutrient Uptake by Membrane Efflux ProteinsJames Thorne
Artificial Intelligence-Driven Protein Design for Studying Cell Signalling and ChromatinElton Zeqiraj
Building the First In Vivo Model of Human Neuron–Microglia InteractionsMarine Krzisch
Engineering Superselective Molecular Probes for Neuronal GlycansBruce Turnbull
Molecular footprints of amyloid aggregation in vivoFrank Sobott
Deconvoluting the sequence determinants for outer membrane protein folding, stability and functionDavid Brockwell
Making and breaking myosin filaments: How smooth muscle cells modulate their contractile behaviourMichelle Peckham
Uncovering the molecular dialogue of on-board acting enzymes in natural product biosynthesisRyan Seipke
Protein Design for Genome Stability: Targeting Key Interfaces in the DNA Damage ResponseQian Wu
Investigating the structural optimisation of bone through computational biomechanical modellingPete Watson
Stopping GLI transcription factors in their tracks: identifying regulators of proteolysis as therapeutic targetsNatalia Riobo-Del Galdo
Decoding and Optimising the Genetics and Structural Biology of Plant Architectural Control for Climate-Resilient Crop ProductionStefan Kepinski
Hijacking Diapause: How Environmental Cues and Pheromones Shape Insect Reproduction in a Changing ClimateElizabeth Duncan
Illuminating the role of ciliary transport factors outside ciliaHelen Foster
It’s getting hot in here – how heatwaves impact health and ageingAmanda Bretman
Structure-guided discovery of selective modulators of brain and cancer-associated potassium channelsJonathan Lippiat
Collaborative Awards in Science and Engineering (CASE)
In situ studies of the mitochondrial respiratory pathway in agriculturally-important pests: an integrated chemical biology and cryo-electron tomography approach. Ste Muench
Next-gen Synbiotic Foods: Novel Fibre Combinations as Modulators of the Gut Microbiome and Gut–Brain Axis Signalling Idolo Ifie
Mapping the Gut Guardians: TraDIS-Guided Genetic Insights into Bifidobacterium Anthony Buckley

University of Sheffield

Click on the project title to view the full description on the FindAPhD website.

ProjectPrimary supervisor
Carbon Capture RiceJulie Gray
Convergence or divergence? Evolution of phagocytosis molecular mechanisms in animal macrophagesSimon Johnson
Deciphering proton shuttling on the surface of biological membranes toward proton translocating channelsNadav Amdbursky
Decoding the epigenetic language shaping root parasite-host communicationSaima Shahid
Defining the Reproductive and Offspring Developmental Impacts of e-CigarettesAdam Watkins
Engineering Stomata: How Shape Informs FunctionAndrew Fleming
ER Phone Home: Defence Signalling from the Endoplasmic Reticulum to the Cell Wall.Jurrian Ton
Evolution of a Gene Regulatory Network Responsible for Avian FlightMatt Towers
Exploring the role of L,D-transpeptidases in the cell envelope remodelling of Rhizobium leguminosarum during symbiosis with legumesStephane Mesnage
From Flies to Fish: Exploring Neural Synchrony in Visual ProcessingMikko Juusola
Genomics and development of an exaggerated sexual trait in stalk-eyed fliesAlison Wright
Harnessing JAK-STAT signalling for optimal innate immune cell functionGillian Tomlinson
How do cells coordinate nutrient scavenging pathways?Jason King
How does Keratin switching enable regenerative cell recruitment to sites of injury?Henry Roehl
How does the Oestrogen receptor globally regulate transcription across the genome during development?Matt Newton
Integrated purification, formulation, and delivery of next-generation mRNA, circRNA, saRNA medicinesZoltan Kis
Life and death in the age of vancomycin: visualising how Clostridioides difficile survives antibiotic treatment at the single cell level.Robert Fagan
Mechanical microenvironment as a regulator of ribosome biogenesis and cell growthKai Erdmann
Mechanisms and exploitation of phage host hijackingPer Bullough
Natural GM: The Role of Horizontal Gene Transfer in Crop Adaptation and EvolutionLuke Dunning
Neuronal compensation for natural circuit perturbationsAndrew Lin
Nuclear Myosin VI supports DNA repair and is a potential therapeutic targetChris Toseland
Paraspeckle condensates in cell health, stress and disease – what can structural studies tell us?Tatyana Shelkovnikova
Predicting pathogen evolution: using experimental evolution to understand the impact of phage therapy on Clostridioides difficileEllie Harrison
Primed for Protection: Cell Wall Modifications in Plant Defence and Long-Term ImmunitySam Amsbury
Rewiring photosynthesis to improve CO2 fixation using synthetic biologyMatt Johnson
Signalling complexes and cell wall changes during plant reproductionLisa Smith
Tackling ageing in the gut: investigating the contribution of macrophages in the intestinal stem cell niche to gut maintenance and repairCatarina Henriques
The Functional Role of rRNA Modifications in Ectoderm DifferentiationEmma Thomson
The genetic and developmental control of complex nanostructure formation in butterfly wing scalesNicola Nadeau
The integrated stress response in ageing: the actions of ATF4Mirre Simons
The needle in the haystack – single molecule detection of extracellular vesicles in complex biological contextsTim Craggs
The role of keratin networks in cell division in tissues under tensionHelen Matthews
The role of long non-coding RNAs in guard cell function and developmentStuart Casson
The role of singlet exciton fission in photosynthesisJenny Clark
Collaborative Awards in Science and Engineering (CASE)
Human Stem Cell-Based Approaches for Neurotoxicity Testing of Environmental ContaminantsIvana Barbaric
Deciphering the mechanism of apicoplast genome organisation in Plasmodium falciparumIndrajit Lahiri
Decoding Condensin Regulation: Single-Molecule Tools to Target IDR InteractionsErin Cutts
Plant protection products as accidental drivers of antimicrobial resistance in agriculture.  Ellie Harrison
Developing cyanobacteria for enhanced light-driven biotechnology Andrew Hitcock

University of York

Click on the project title to view the full description on the FindAPhD website.

ProjectPrimary supervisor
Chemical-warfare-in-the-rhizosphere-unpicking-the-defensive-role-of-plant-root-exudates-against-the-bacterial-pathogen-ralstonia-solanacearumAndrea Harper
Investigating-the-co2-concentrating-mechanism-in-haptophyte-algaeCharlotte Walker
Pseudoknot-or-riboswitch-structures-and-dynamics-of-viral-rna-elements-that-control-programmed-ribosomal-frameshiftingChris Hill
Real-time-single-molecule-imaging-of-pathological-translation-events-in-viral-infectionChristoph Baumman
Life-pushed-to-extremes-probing-the-mechanisms-of-chromosome-segregation-in-thermophilic-archaeaDaniela Barilla
Variation-in-how-plants-absorb-metals-from-nutritious-vegetables-to-phytominingDaphne Ezer
Death-hunters-impact-of-cell-death-modalities-on-phagocyte-proteostasis-and-innate-signallingDave Boucher
How-do-plants-feel-the-cool-of-evening-and-use-it-to-time-growthSeth Davis
Epigenetics-and-evolution-at-the-frontline-of-plant-chemical-defenceBenjamin Lichman
Making-sense-of-antigenic-variation-in-trypanosomes-a-nuclear-factory-with-a-switching-and-replication-problemJoana Correiafaria
New-ccl5-prosthesis-and-photo-crosslinking-approach-for-functional-analysis-of-low-density-endogenous-ccr5-receptorsNathalie Signoret
Holding-on-investigating-the-contribution-of-attached-leishmania-parasite-forms-in-human-infectionsNicola Baker
Predicting-the-next-pandemic-by-enhancing-viral-surveillanceDaniel Jeffares
Deciphering-phagosome-biology-during-leishmania-infection-with-ultrasensitive-proteomicsElmarie Myburgh
Breaking-the-surface-of-pseudomonas-elucidation-of-the-biochemical-basis-of-pseudaminic-acid-transport-and-catabolism-in-bacteriaGavin Thomas
Space-matters-how-does-gsk3-orchestrate-glial-development-and-functionInes Hahn
Fire-in-the-neighbourhood-investigating-how-environment-and-experience-shape-inflammatory-responsesJames Hewitson
Applying-synthetic-biology-tools-to-the-black-soldier-fly-for-sustainable-food-and-feed-systemsJoshua Ang
Magic-crops-genomics-to-breed-high-yielding-resilient-and-nutritious-amaranthKatherine Denby
Understanding-caspase-14-how-it-helps-keep-our-skin-healthy-and-heals-woundsKim Robinson
Using-plants-for-green-recovery-of-technology-critical-rare-earth-elements-from-wastesLiz Rylott
Engineering-synthetic-organelles-in-algae-for-biotechnologyLuke Mackinder
Agents-of-change-an-exploration-of-how-viruses-and-viriforms-shape-bacterial-evolution-fitness-and-antibiotic-resistancePaul Fogg
A-farewell-to-arms-the-trade-off-between-growth-and-defence-in-bacteriaSean Meaden
Microalgae-as-green-biofactories-for-insect-pheromone-productionThierry Tonon
AI-driven-bacteriophage-design-to-combat-antibiotic-resistant-pathogensOliver Bayfield
Electrochemical-dissection-of-the-succinate-dehydrogenases-that-allow-survival-of-mycobacterium-tuberculosis-during-pathophysiological-oxygen-shiftsAlison Parkin
Chemical-protein-modification-for-isotope-labellingChris Spicer
Structural-virology-of-viral-dark-matter-assembly-and-infection-mechanisms-of-archaeal-virusesFred Antson
Creating-a-molecular-movie-of-carbon-fixation-by-rubisco-with-time-resolved-cryo-emJamie Blaza
Engineering-orthogonal-cytokine-receptor-pairs-via-ring-expanding-protein-bioconjugation-and-chemical-biologyWilliam Unsworth
Collaborative Awards in Science and Engineering (CASE)
Pushing-energy-efficient-urban-farming-to-the-limit-using-plant-circadian-clocksDaphne Ezer
Purification-of-protein-biologics-via-affinity-tagged-biomolecular-condensatesMichael Plevin
Developing-microbial-upflow-anaerobic-sludge-blanket-uasb-reactors-for-biogas-fuel-and-chemical-production-from-wastewaterMatthew Reilly
Decoding-human-blood-stem-cells-proteomics-and-super-resolution-imaging-of-cellular-adaptationWilliam Grey
Developing-novel-insecticidal-proteins-for-crop-protectionFederico Sabbadin
Discovering-conserved-transcriptional-networks-driving-plant-immunityKatherine Denby
A-synthetic-biology-approach-to-local-gene-drives-in-aedes-aegyptiLuke Alphey
Understanding-co2-fluxes-in-algae-to-enhance-biotechnology-applicationsLuke Mackinder

Find more information about funding and eligibility on How to apply.